Rome's Jewish Ghetto is the world's second oldest after Venice, home to Europe's oldest Jewish community for 2,200 years. The neighborhood features the magnificent Great Synagogue built in 1904, the Jewish Museum, and the ancient Portico of Octavia. The area is famous for its Jewish-Roman restaurants serving specialties like carciofi alla giudia (fried artichokes). A walking tour reveals layers of history from ancient Rome through Renaissance persecution to modern revival.